Indianapolis Colts vs Jacksonville Jaguars Prediction & Odds
· EverBank Stadium
- Indianapolis Colts at Jacksonville Jaguars: kickoff Sunday, November 1, 2026 at 1:00 PM ET, EverBank Stadium.
- Spread: Jaguars -7.5, the median of 15 sportsbooks. Best available: Colts +7.5 (-110, BetMGM) · Jaguars -7.5 (-106, Caesars).
- Total (over/under): 46.5. Best available: Over 46.5 (-110, Caesars) · Under 47 (-110, Circa).
- Best moneyline: Colts (+350, FanDuel) · Jaguars (-380, Caesars).
- Lines as of Mon, Oct 26 · 1:37 AM ET; they move after that.
Colts vs Jaguars odds
Best available moneyline, spread and total across 15 sportsbooks. Every book is one tap away.
Indianapolis Colts
+350
FanDuel
+7.5 -110
BetMGM
O 46.5 -110
Caesars
Jacksonville Jaguars
-380
Caesars
-7.5 -106
Caesars
U 47.0 -110
Circa
View all sportsbooks (15)Eligible fresh comparisons
Bally Bet
+335-435
+7.5 -114-7.5 -107
O 46.5 -114U 46.5 -107
BetMGM
+320-400
+7.5 -110-7.5 -108
——
BetR Sportsbook
+310-417
——
——
BetRivers
+335-435
+7.5 -114-7.5 -107
O 46.5 -114U 46.5 -107
Caesars
+295-380
+7.5 -114-7.5 -106
O 46.5 -110U 46.5 -110
Circa
+310-380
+7.5 -110-7.5 -110
O 47.0 -110U 47.0 -110
DraftKings
+300-380
+7.5 -112-7.5 -108
O 46.5 -110U 46.5 -110
ESPN BET
+340-450
+7.5 -110-7.5 -110
O 46.5 -115U 46.5 -105
Fanatics
+310-400
——
O 46.5 -115U 46.5 -105
FanDuel
+350-450
+7.5 -110-7.5 -110
O 46.5 -115U 46.5 -105
Hard Rock Bet
+300-400
+7.5 -110-7.5 -110
O 47.0 -110U 47.0 -110
PointsBet
+330-417
+7.5 -111-7.5 -111
——
theScore Bet
+340-450
+7.5 -110-7.5 -110
O 46.5 -115U 46.5 -105
◆ Best: the most favorable fresh line, then price, for that exact side. Rows read Indianapolis Colts first, then Jacksonville Jaguars.
Colts vs Jaguars AI prediction
The KarmaEdge AI spread and total projections next to the posted line, with the KarmaEdge AI Score.
Colts vs Jaguars line movement
DraftKings lines from the open (or the first line KarmaEdge tracked) to now.
| Market | Side | Open / first tracked | Now | Move |
|---|---|---|---|---|
| Moneyline | Colts | 180.0 Open | 300.0 | +120 |
| Moneyline | Jaguars | -218.0 Open | -380.0 | -162 |
| Spread | Colts | 4.5 Open | 7.5 | +3 |
| Spread | Jaguars | -4.5 Open | -7.5 | -3 |
| Total | Over | 49.5 Open | 46.5 | -3 |
| Total | Under | 49.5 Open | 46.5 | -3 |
Colts vs Jaguars on the field
Each team's listed starters in its base formation, from the depth charts as of Oct 25, 2026. Tap a player for the backups.
Jaguars defense · Base 4-3
- #92 Danny Striggow
- #90 Wesley Williams
- #95 B.J. Green II
- #93 Matt Dickerson
- #99 Ruke Orhorhoro
- #98 Albert Regis
- #57 Bryan Thomas Jr.
- #58 Zach Durfee
- #31 Jahlani Tavai
- #50 Branson Combs
- #53 Parker Hughes
- #35 Jalen McLeod
- #45 Jared Bartlett
- Jaylon Jones Q
- #25 Rayuan Lane III
- #22 Jalen Huskey
- #26 Kaevon Merriweather
- #27 Caleb Ransaw
- #4 Jarrian Jones
- #21 Alijah Huzzie
- #5 Anthony Richardson Sr.
- #15 Riley Leonard
- #20 Seth McGowan
- #21 DJ Giddens
- #16 Ashton Dulin
- #14 Alec Pierce
- #80 Deion Burks
- #3 D.J. Montgomery
- #6 Anthony Gould O
- #86 Will Mallory
- #81 Mo Alie-Cox
- #85 Drew Ogletree
- #68 Dalton Tucker
- #63 Sedrick Van Pran-Granger
- #62 Jalen Farmer
- #67 Luke Tenuta
Colts offense · 11 personnel
Colts defense · Base 4-3
- #52 George Gumbs Jr.
- #98 Arden Key
- #95 Adetomiwa Adebawore
- #94 Jerry Tillery
- #93 Tim Smith
- #55 Caden Curry
- #72 Micheal Clemons
- #44 Tahj Chambers
- #53 CJ Allen O
- #53 Germaine Pratt
- #58 Austin Ajiake
- Kenneth Harris
- #43 Cameron Mitchell
- #30 Hunter Wohler
- #38 Jonathan Owens
- #29 Cam Taylor-Britt
- #10 Quinn Ewers
- #24 Chris Rodriguez Jr.
- #5 LeQuint Allen Jr.
- #20 Ameer Abdullah
- #7 Brian Thomas Jr.
- #12 Travis Hunter
- #18 CJ Williams
- #87 Nate Boerkircher
- #88 Tanner Koziol
- #80 Quintin Morris
- #77 Anton Harrison
- #68 Daniel Faalele
- #74 Garrett DiGiorgio
- #60 Jonah Monheim
- #69 Sam Mustipher
- #64 Wyatt Milum
- #65 Patrick Mekari
- #72 Walker Little
Jaguars offense · 11 personnel
Indianapolis Colts depth chart → Jacksonville Jaguars depth chart →
Colts vs Jaguars injury report
This game's injury reports are not out yet. The depth charts below carry each team's latest report.
Indianapolis Colts depth chart → Jacksonville Jaguars depth chart →
Frequently asked questions
What time is Colts vs Jaguars?
Kickoff is Sunday, November 1, 2026 at 1:00 PM ET at EverBank Stadium.
What is the spread for Colts vs Jaguars?
The median spread across 15 sportsbooks is Jaguars -7.5 as of Mon, Oct 26 · 1:37 AM ET. Best available by side: Colts +7.5 (-110, BetMGM) · Jaguars -7.5 (-106, Caesars).
What is the over/under for Colts vs Jaguars?
The median total across 15 sportsbooks is 46.5. Best available: Over 46.5 (-110, Caesars) · Under 47 (-110, Circa).
What are the moneyline odds for Colts vs Jaguars?
The best available moneylines are Colts (+350, FanDuel) · Jaguars (-380, Caesars).
Does KarmaEdge have an AI prediction for Colts vs Jaguars?
Not yet. No KarmaEdge AI projection is published for Colts vs Jaguars; games appear once the model is published for the slate. Nothing is filled in meanwhile.
Is KarmaEdge.AI a sportsbook?
No. KarmaEdge.AI is not a sportsbook and never accepts wagers. It is a research site that compares markets and shows KarmaEdge AI research next to them.
KarmaEdge.AI is not a sportsbook and never accepts wagers. Lines move; each shows when it was read. Projections are research, not guarantees. 18+ and of legal age where you are. Gambling problem? Call 1-800-GAMBLER.
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