Dallas Cowboys vs Indianapolis Colts Prediction & Odds
· Lucas Oil Stadium
- Dallas Cowboys at Indianapolis Colts: kickoff Sunday, November 8, 2026 at 1:00 PM ET, Lucas Oil Stadium.
- Spread: Cowboys -5.5, the median of 15 sportsbooks. Best available: Cowboys -5.5 (-107, Caesars) · Colts +6.5 (-110, Circa).
- Total (over/under): 51.5. Best available: Over 51.5 (-109, Caesars) · Under 52 (-110, Fanatics).
- Best moneyline: Cowboys (-245, Fanatics) · Colts (+235, Circa).
- Lines as of Mon, Nov 2 · 3:11 AM ET; they move after that.
Cowboys vs Colts odds
Best available moneyline, spread and total across 15 sportsbooks. Every book is one tap away.
Dallas Cowboys
-245
Fanatics
-5.5 -107
Caesars
O 51.5 -109
Caesars
Indianapolis Colts
+235
Circa
+6.5 -110
Circa
U 52.0 -110
Fanatics
View all sportsbooks (15)Eligible fresh comparisons
Bally Bet
-278+225
-5.5 -114+5.5 -107
——
BetMGM
-275+210
-6.0 -108+6.0 -110
O 51.5 -110U 51.5 -108
BetR Sportsbook
-263+205
——
——
BetRivers
-278+225
-5.5 -114+5.5 -106
——
Caesars
-265+210
-5.5 -107+5.5 -113
O 51.5 -109U 51.5 -112
Circa
-280+235
-6.5 -110+6.5 -110
——
DraftKings
-258+210
——
O 51.5 -110U 51.5 -110
ESPN BET
-270+220
-5.5 -110+5.5 -110
O 51.5 -110U 51.5 -110
Fanatics
-245+200
-5.5 -110+5.5 -110
O 52.0 -110U 52.0 -110
FanDuel
-260+215
-5.5 -110+5.5 -110
O 51.5 -110U 51.5 -110
Hard Rock Bet
-260+210
-5.5 -110+5.5 -110
O 52.0 -110U 52.0 -110
PointsBet
-250+210
-5.5 -115+5.5 -105
O 51.5 -111U 51.5 -111
theScore Bet
-270+220
-5.5 -110+5.5 -110
O 51.5 -110U 51.5 -110
◆ Best: the most favorable fresh line, then price, for that exact side. Rows read Dallas Cowboys first, then Indianapolis Colts.
Cowboys vs Colts AI prediction
The KarmaEdge AI spread and total projections next to the posted line, with the KarmaEdge AI Score.
Cowboys vs Colts line movement & betting splits
DraftKings lines from the open (or the first line KarmaEdge tracked) to now. Bet % and Money % appear only where verified splits are available.
| Market | Side | Open / first tracked | Now | Move | Bet % | Money % |
|---|---|---|---|---|---|---|
| Moneyline | Cowboys | -125.0 Open | -258.0 | -133 | 82% | 88% |
| Moneyline | Colts | 105.0 Open | 210.0 | +105 | 18% | 12% |
| Total | Over | 52.5 Open | 51.5 | -1 | — | — |
| Total | Under | 52.5 Open | 51.5 | -1 | — | — |
Cowboys vs Colts on the field
Each team's listed starters in its base formation, from the depth charts as of Nov 1, 2026. Tap a player for the backups.
Colts defense · Base 4-3
- #52 George Gumbs Jr.
- #98 Arden Key
- #93 Tim Smith
- #90 Kevin Givens
- #94 Jerry Tillery
- #55 Caden Curry
- #96 Carl Lawson
- #72 Micheal Clemons
- #57 Jaylon Carlies
- #44 Tahj Chambers
- #58 Austin Ajiake
- Kenneth Harris
- #43 Cameron Mitchell
- #30 Hunter Wohler
- #38 Jonathan Owens
- #35 Johnathan Edwards
- #29 Cam Taylor-Britt
- #16 Sam Howell
- #32 Tyler Goodson
- #20 Malik Davis
- #9 KaVontae Turpin O
- #18 Jonathan Mingo
- #80 Camden Brown
- #89 Brevyn Spann-Ford
- #86 Luke Schoonmaker Q
- #84 James Mitchell
- #67 Drew Shelton
- #66 T.J. Bass
- #72 Matt Hennessy
- #65 Ajani Cornelius
- #77 Broderick Jones
Cowboys offense · 11 personnel
Cowboys defense · Base 3-4
- #99 LT Overton
- #90 Jonathan Bullard Q
- #93 Elijah Garcia
- #94 Kelvin Gilliam Jr.
- #40 Von Miller
- #41 James Houston
- #55 Jaishawn Barham
- #50 Shemar James
- #45 Justin Barron
- #57 Malachi Lawrence
- #59 Tyrus Wheat
- #35 Marist Liufau Q
- #2 Cobie Durant
- #29 Devin Moore
- #14 Markquese Bell
- #34 Jalen Thompson
- #1 P.J. Locke Q
- #11 Alijah Clark
- #43 Juanyeh Thomas
- #23 Ameer Speed
- #28 Shavon Revel Jr.
- #5 Anthony Richardson Sr.
- #15 Riley Leonard
- #20 Seth McGowan
- #21 DJ Giddens
- #16 Ashton Dulin
- #14 Alec Pierce
- #80 Deion Burks
- #3 D.J. Montgomery
- #6 Anthony Gould O
- #86 Will Mallory
- #81 Mo Alie-Cox
- #85 Drew Ogletree Q
- #73 Charlie Heck
- #68 Dalton Tucker
- #63 Sedrick Van Pran-Granger
- #62 Jalen Farmer
- #67 Luke Tenuta
Colts offense · 11 personnel
Dallas Cowboys depth chart → Indianapolis Colts depth chart →
Cowboys vs Colts injury report
This game's injury reports are not out yet. The depth charts below carry each team's latest report.
Dallas Cowboys depth chart → Indianapolis Colts depth chart →
Frequently asked questions
What time is Cowboys vs Colts?
Kickoff is Sunday, November 8, 2026 at 1:00 PM ET at Lucas Oil Stadium.
What is the spread for Cowboys vs Colts?
The median spread across 15 sportsbooks is Cowboys -5.5 as of Mon, Nov 2 · 3:11 AM ET. Best available by side: Cowboys -5.5 (-107, Caesars) · Colts +6.5 (-110, Circa).
What is the over/under for Cowboys vs Colts?
The median total across 15 sportsbooks is 51.5. Best available: Over 51.5 (-109, Caesars) · Under 52 (-110, Fanatics).
What are the moneyline odds for Cowboys vs Colts?
The best available moneylines are Cowboys (-245, Fanatics) · Colts (+235, Circa).
Does KarmaEdge have an AI prediction for Cowboys vs Colts?
Not yet. No KarmaEdge AI projection is published for Cowboys vs Colts; games appear once the model is published for the slate. Nothing is filled in meanwhile.
Is KarmaEdge.AI a sportsbook?
No. KarmaEdge.AI is not a sportsbook and never accepts wagers. It is a research site that compares markets and shows KarmaEdge AI research next to them.
KarmaEdge.AI is not a sportsbook and never accepts wagers. Lines move; each shows when it was read. Projections are research, not guarantees. 18+ and of legal age where you are. Gambling problem? Call 1-800-GAMBLER.
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