NFL · Prediction, odds & props

Denver Broncos vs Arizona Cardinals Prediction & Odds

· State Farm Stadium

Quick answer
  • Denver Broncos at Arizona Cardinals: kickoff Sunday, October 25, 2026 at 4:05 PM ET, State Farm Stadium.
  • Spread: Broncos -4.5, the median of 14 sportsbooks. Best available: Broncos -4.5 (-108, BetMGM) · Cardinals +4.5 (-108, Tipico).
  • Total (over/under): 43.5. Best available: Over 43.5 (-105, ESPN BET) · Under 44 (-110, BetMGM).
  • Best moneyline: Broncos (-220, Hard Rock Bet) · Cardinals (+195, Circa).
  • Lines as of Mon, Oct 19 · 2:44 PM ET; they move after that.

Broncos vs Cardinals odds

Best available moneyline, spread and total across 14 sportsbooks. Every book is one tap away.

2:44 PM ET
14 booksMoneylineSpreadTotal
Denver Broncos -220 Hard Rock Bet -4.5 -108 BetMGM O 43.5 -105 ESPN BET
Arizona Cardinals +195 Circa +4.5 -108 Tipico U 44.0 -110 BetMGM
View all sportsbooks (14)Eligible fresh comparisons
BookMoneylineSpreadTotal
Bally Bet -230+180 -4.5 -109+4.5 -114 O 43.5 -108U 43.5 -114
BetMGM -225+188 -4.5 -108+4.5 -110 O 44.0 -108U 44.0 -110
BetR Sportsbook -233+185 —— ——
BetRivers -230+180 -4.5 -109+4.5 -114 O 43.5 -108U 43.5 -114
Caesars -225+186 -4.5 -108+4.5 -112 O 43.5 -110U 43.5 -110
Circa -225+195 —— O 44.0 -110U 44.0 -110
DraftKings -230+190 -4.5 -110+4.5 -110 O 43.5 -112U 43.5 -108
ESPN BET -230+195 -4.5 -110+4.5 -110 O 43.5 -105U 43.5 -115
FanDuel -240+194 -4.5 -110+4.5 -110 O 43.5 -110U 43.5 -110
Hard Rock Bet -220+180 -4.5 -110+4.5 -110 O 43.5 -110U 43.5 -110
PointsBet -227+185 -4.5 -111+4.5 -111 O 43.5 -111U 43.5 -111
SugarHouse -230+180 -4.5 -109+4.5 -114 O 43.5 -108U 43.5 -114
theScore Bet -230+195 -4.5 -110+4.5 -110 O 43.5 -105U 43.5 -115
Tipico -238+180 -4.5 -120+4.5 -108 O 43.5 -115U 43.5 -111

◆ Best: the most favorable fresh line, then price, for that exact side. Rows read Denver Broncos first, then Arizona Cardinals.

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Broncos vs Cardinals AI prediction

The KarmaEdge AI spread and total projections next to the posted line, with the KarmaEdge AI Score.

No KarmaEdge AI projection is published for this game yetGames appear once the KarmaEdge AI model is published for the slate. Nothing is filled in meanwhile.

All NFL AI predictions →

Broncos vs Cardinals line movement & betting splits

DraftKings lines from the open (or the first line KarmaEdge tracked) to now. Bet % and Money % appear only where verified splits are available.

MarketSideOpen / first trackedNowMoveBet %Money %
MoneylineBroncos -355.0 Open -230.0 +125 92%70%
MoneylineCardinals 280.0 Open 190.0 -90 8%30%
SpreadBroncos -7.5 Open -4.5 +3 89%89%
SpreadCardinals 7.5 Open 4.5 -3 11%11%
TotalOver 43.5 Open 43.5 0 67%21%
TotalUnder 43.5 Open 43.5 0 33%79%

Every NFL line move on Live Trends →

Frequently asked questions

What time is Broncos vs Cardinals?

Kickoff is Sunday, October 25, 2026 at 4:05 PM ET at State Farm Stadium.

What is the spread for Broncos vs Cardinals?

The median spread across 14 sportsbooks is Broncos -4.5 as of Mon, Oct 19 · 2:44 PM ET. Best available by side: Broncos -4.5 (-108, BetMGM) · Cardinals +4.5 (-108, Tipico).

What is the over/under for Broncos vs Cardinals?

The median total across 14 sportsbooks is 43.5. Best available: Over 43.5 (-105, ESPN BET) · Under 44 (-110, BetMGM).

What are the moneyline odds for Broncos vs Cardinals?

The best available moneylines are Broncos (-220, Hard Rock Bet) · Cardinals (+195, Circa).

Does KarmaEdge have an AI prediction for Broncos vs Cardinals?

Not yet. No KarmaEdge AI projection is published for Broncos vs Cardinals; games appear once the model is published for the slate. Nothing is filled in meanwhile.

Is KarmaEdge.AI a sportsbook?

No. KarmaEdge.AI is not a sportsbook and never accepts wagers. It is a research site that compares markets and shows KarmaEdge AI research next to them.

KarmaEdge.AI is not a sportsbook and never accepts wagers. Lines move; each shows when it was read. Projections are research, not guarantees. 18+ and of legal age where you are. Gambling problem? Call 1-800-GAMBLER.