USC vs Indiana Prediction & Odds
USC vs Indiana AI prediction
The KarmaEdge AI spread and total projections next to the posted line, with the KarmaEdge AI Score.
USC vs Indiana odds
Best available moneyline, spread and total across 13 sportsbooks. Every book is one tap away.
USC
+225
ESPN BET
+7.5 -115
Bally Bet
O 49.5 +100
Bally Bet
Indiana
-265
Caesars
-7.0 -112
BetMGM
U 49.5 -110
BetMGM
View all sportsbooks (13)Eligible fresh comparisons
Bally Bet
+220-286
+7.5 -115-7.5 -106
O 49.5 +100U 49.5 -122
BetMGM
+210-275
+7.0 -105-7.0 -112
O 49.5 -108U 49.5 -110
BetR Sportsbook
+215-286
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BetRivers
+220-286
+7.5 -117-7.5 -107
O 49.5 +100U 49.5 -122
Caesars
+215-265
+7.5 -118-7.5 -102
O 49.5 -112U 49.5 -112
DraftKings
+220-270
+7.0 -105-7.0 -115
O 49.5 -105U 49.5 -115
ESPN BET
+225-275
+7.5 -115-7.5 -105
O 49.5 -105U 49.5 -115
Fanatics
+220-275
+7.5 -115-7.5 -105
O 49.5 -110U 49.5 -110
FanDuel
+215-265
+7.5 -124-7.5 +102
O 49.5 -110U 49.5 -110
Hard Rock Bet
+220-275
+7.5 -115-7.5 -105
O 49.5 +100U 49.5 -120
PointsBet
+210-270
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theScore Bet
+225-278
+7.5 -115-7.5 -105
O 49.5 -105U 49.5 -115
◆ Best: the most favorable fresh line, then price, for that exact side. Rows read USC first, then Indiana.
USC vs Indiana line movement & betting splits
DraftKings lines from the open (or the first line KarmaEdge tracked) to now. Bet % and Money % appear only where verified splits are available.
| Market | Side | Open / first tracked | Now | Move | Bet % | Money % |
|---|---|---|---|---|---|---|
| Moneyline | USC | 230.0 Open | 220.0 | -10 | 3% | 14% |
| Moneyline | Indiana | -285.0 Open | -270.0 | +15 | 97% | 86% |
| Spread | USC | 7.0 Open | 7.0 | 0 | 42% | 75% |
| Spread | Indiana | -7.0 Open | -7.0 | 0 | 58% | 25% |
| Total | Over | 50.5 Open | 49.5 | -1 | — | — |
| Total | Under | 50.5 Open | 49.5 | -1 | — | — |
Frequently asked questions
What time is USC vs Indiana?
Kickoff is Saturday, November 14, 2026 at 2:30 PM ET.
What is the spread for USC vs Indiana?
The median spread across 13 sportsbooks is Indiana -7.5 as of Sun, Nov 8 · 2:51 PM ET. Best available by side: USC +7.5 (-115, Bally Bet) · Indiana -7 (-112, BetMGM).
What is the over/under for USC vs Indiana?
The median total across 13 sportsbooks is 49.5. Best available: Over 49.5 (+100, Bally Bet) · Under 49.5 (-110, BetMGM).
What are the moneyline odds for USC vs Indiana?
The best available moneylines are USC (+225, ESPN BET) · Indiana (-265, Caesars).
Does KarmaEdge have an AI prediction for USC vs Indiana?
Not yet. No KarmaEdge AI projection is published for USC vs Indiana; games appear once the model is published for the slate. Nothing is filled in meanwhile.
Is KarmaEdge.AI a sportsbook?
No. KarmaEdge.AI is not a sportsbook and never accepts wagers. It is a research site that compares markets and shows KarmaEdge AI research next to them.
KarmaEdge.AI is not a sportsbook and never accepts wagers. Lines move; each shows when it was read. Projections are research, not guarantees. 18+ and of legal age where you are. Gambling problem? Call 1-800-GAMBLER.
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