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Clemson vs Syracuse Prediction & Odds

Quick answer
  • Clemson at Syracuse: kickoff Saturday, November 7, 2026 at 11:00 AM ET.
  • Spread: Clemson -3.5, the median of 4 sportsbooks. Best available: Clemson -3.5 (-105, FanDuel) · Syracuse +3.5 (-115, FanDuel).
  • Total (over/under): 48.5. Best available: Over 48.5 (-110, Fanatics) · Under 48.5 (-110, Fanatics).
  • Best moneyline: Clemson (-155, Fanatics) · Syracuse (+130, Fanatics).
  • Lines as of Sun, Nov 1 · 4:29 AM ET; they move after that.

Clemson vs Syracuse odds

Best available moneyline, spread and total across 4 sportsbooks. Every book is one tap away.

4:29 AM ET
4 booksMoneylineSpreadTotal
Clemson -155 Fanatics -3.5 -105 FanDuel O 48.5 -110 Fanatics
Syracuse +130 Fanatics +3.5 -115 FanDuel U 48.5 -110 Fanatics
View all sportsbooks (4)Eligible fresh comparisons
BookMoneylineSpreadTotal
BetR Sportsbook -164+125 —— ——
Fanatics -155+130 —— O 48.5 -110U 48.5 -110
FanDuel -156+130 -3.5 -105+3.5 -115 O 48.5 -110U 48.5 -110
PointsBet -159+130 —— ——

◆ Best: the most favorable fresh line, then price, for that exact side. Rows read Clemson first, then Syracuse.

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Clemson vs Syracuse AI prediction

The KarmaEdge AI spread and total projections next to the posted line, with the KarmaEdge AI Score.

No KarmaEdge AI projection is published for this game yetGames appear once the KarmaEdge AI model is published for the slate. Nothing is filled in meanwhile.

All College football AI predictions →

Frequently asked questions

What time is Clemson vs Syracuse?

Kickoff is Saturday, November 7, 2026 at 11:00 AM ET.

What is the spread for Clemson vs Syracuse?

The median spread across 4 sportsbooks is Clemson -3.5 as of Sun, Nov 1 · 4:29 AM ET. Best available by side: Clemson -3.5 (-105, FanDuel) · Syracuse +3.5 (-115, FanDuel).

What is the over/under for Clemson vs Syracuse?

The median total across 4 sportsbooks is 48.5. Best available: Over 48.5 (-110, Fanatics) · Under 48.5 (-110, Fanatics).

What are the moneyline odds for Clemson vs Syracuse?

The best available moneylines are Clemson (-155, Fanatics) · Syracuse (+130, Fanatics).

Does KarmaEdge have an AI prediction for Clemson vs Syracuse?

Not yet. No KarmaEdge AI projection is published for Clemson vs Syracuse; games appear once the model is published for the slate. Nothing is filled in meanwhile.

Is KarmaEdge.AI a sportsbook?

No. KarmaEdge.AI is not a sportsbook and never accepts wagers. It is a research site that compares markets and shows KarmaEdge AI research next to them.

KarmaEdge.AI is not a sportsbook and never accepts wagers. Lines move; each shows when it was read. Projections are research, not guarantees. 18+ and of legal age where you are. Gambling problem? Call 1-800-GAMBLER.