Las Vegas Raiders vs San Francisco 49ers Prediction & Odds
· Levi's Stadium
- Las Vegas Raiders at San Francisco 49ers: kickoff Sunday, November 8, 2026 at 4:25 PM ET, Levi's Stadium.
- Spread: 49ers -9.5, the median of 15 sportsbooks. Best available: Raiders +9.5 (-105, Tipico) · 49ers -9 (-110, Hard Rock Bet).
- Total (over/under): 51.5. Best available: Over 51 (-110, Circa) · Under 51.5 (-105, PointsBet).
- Best moneyline: Raiders (+410, FanDuel) · 49ers (-450, Fanatics).
- Lines as of Mon, Nov 2 · 3:11 AM ET; they move after that.
Raiders vs 49ers odds
Best available moneyline, spread and total across 15 sportsbooks. Every book is one tap away.
Las Vegas Raiders
+410
FanDuel
+9.5 -105
Tipico
O 51.0 -110
Circa
San Francisco 49ers
-450
Fanatics
-9.0 -110
Hard Rock Bet
U 51.5 -105
PointsBet
View all sportsbooks (15)Eligible fresh comparisons
Bally Bet
+405-560
+9.5 -109-9.5 -112
O 51.0 -114U 51.0 -107
BetMGM
+400-500
+9.5 -108-9.5 -110
O 51.5 -108U 51.5 -110
BetR Sportsbook
+375-526
——
——
BetRivers
+405-560
+9.5 -109-9.5 -112
O 51.0 -114U 51.0 -107
Caesars
+375-480
+9.5 -107-9.5 -113
O 51.5 -112U 51.5 -109
Circa
+385-485
+9.5 -110-9.5 -110
O 51.0 -110U 51.0 -110
DraftKings
+380-500
+9.5 -110-9.5 -110
O 51.5 -105U 51.5 -115
ESPN BET
+360-500
+9.5 -110-9.5 -110
O 51.5 -110U 51.5 -110
Fanatics
+340-450
+9.5 -110-9.5 -110
O 51.5 -110U 51.5 -110
FanDuel
+410-550
+9.5 -106-9.5 -114
O 51.5 -110U 51.5 -110
Hard Rock Bet
+375-500
+9.0 -110-9.0 -110
O 51.5 -110U 51.5 -110
PointsBet
+350-455
+9.5 -111-9.5 -111
O 51.5 -115U 51.5 -105
theScore Bet
+360-500
+9.5 -110-9.5 -110
O 51.5 -110U 51.5 -110
◆ Best: the most favorable fresh line, then price, for that exact side. Rows read Las Vegas Raiders first, then San Francisco 49ers.
Raiders vs 49ers AI prediction
The KarmaEdge AI spread and total projections next to the posted line, with the KarmaEdge AI Score.
Raiders vs 49ers line movement & betting splits
DraftKings lines from the open (or the first line KarmaEdge tracked) to now. Bet % and Money % appear only where verified splits are available.
| Market | Side | Open / first tracked | Now | Move | Bet % | Money % |
|---|---|---|---|---|---|---|
| Moneyline | Raiders | 330.0 Open | 380.0 | +50 | 23% | 57% |
| Moneyline | 49ers | -425.0 Open | -500.0 | -75 | 77% | 43% |
| Spread | Raiders | 8.5 Open | 9.5 | +1 | 27% | 4% |
| Spread | 49ers | -8.5 Open | -9.5 | -1 | 73% | 96% |
| Total | Over | 46.5 Open | 51.5 | +5 | — | — |
| Total | Under | 46.5 Open | 51.5 | +5 | — | — |
Raiders vs 49ers on the field
Each team's listed starters in its base formation, from the depth charts as of Nov 1, 2026. Tap a player for the backups.
49ers defense · Base 4-3
- #94 Romello Height
- #47 Khalid Kareem
- #91 Sam Okuayinonu
- #55 Sebastian Valdez
- #99 C.J. West
- #93 Gracen Halton
- James Thompson Jr.
- #95 Alfred Collins
- #98 Mykel Williams
- #50 Andrew Farmer II
- #49 Garret Wallow O
- #48 Tatum Bethune
- #45 Nick Martin
- #51 Luke Gifford O
- #6 Malik Mustapha
- #33 Siran Neal Q
- #24 Ashtyn Davis
- #29 Darrick Forrest
- #28 Ephesians Prysock
- #22 Nate Hobbs
- #15 Fernando Mendoza
- #12 Aidan O'Connell
- #4 Mike Washington Jr.
- #23 Dylan Laube
- #33 Chris Collier
- #82 Cody White
- #81 Dareke Young
- #10 Dont'e Thornton Jr.
- #19 Malik Benson
- #87 Michael Mayer
- #80 Ian Thomas
- #84 Carter Runyon O
- #60 Charles Grant
- #77 Bryce Cabeldue
- #66 Trey Zuhn III
- #58 Jackson Powers-Johnson Q
- #77 Justin Pickett
- #66 Trey Zuhn III
- #78 Dalton Wagner
Raiders offense · 11 personnel
Raiders defense · Base 3-4
- #91 Tim Keenan III
- #92 JJ Pegues
- #99 Thomas Booker IV
- #51 Malcolm Koonce
- #42 Keyron Crawford
- #54 Brennan Jackson
- #44 Tommy Eichenberg
- #50 Segun Olubi
- #55 Cody Lindenberg
- #48 Cian Slone
- #93 Patrick Johnson O
- #28 Jermod McCoy
- #25 Darrell Luter Jr.
- #43 Dalton Johnson
- #20 Isaiah Pola-Mao
- #27 Tristin McCollum
- #35 Hezekiah Masses
- #29 Chigozie Anusiem
- #10 Mac Jones
- #14 Kurtis Rourke
- #26 Kaelon Black
- #29 Jordan James
- #31 Isaac Guerendo
- #84 Brandin Cooks
- #11 Demarcus Robinson
- Brandon Aiyuk
- #3 Christian Kirk Q
- #7 De'Zhaun Stribling
- #4 Jacob Cowing
- #1 Ricky Pearsall
- #89 Luke Farrell
- #9 Brayden Willis
- #88 Jake Tonges
- #76 Vederian Lowe
- #69 Enrique Cruz Jr.
- #62 Austen Pleasants
- #74 Carver Willis
- #63 Nick Zakelj
- #58 Jarrett Patterson
- #74 Carver Willis
- #69 Enrique Cruz Jr.
49ers offense · 11 personnel
Las Vegas Raiders depth chart → San Francisco 49ers depth chart →
Raiders vs 49ers injury report
This game's injury reports are not out yet. The depth charts below carry each team's latest report.
Las Vegas Raiders depth chart → San Francisco 49ers depth chart →
Frequently asked questions
What time is Raiders vs 49ers?
Kickoff is Sunday, November 8, 2026 at 4:25 PM ET at Levi's Stadium.
What is the spread for Raiders vs 49ers?
The median spread across 15 sportsbooks is 49ers -9.5 as of Mon, Nov 2 · 3:11 AM ET. Best available by side: Raiders +9.5 (-105, Tipico) · 49ers -9 (-110, Hard Rock Bet).
What is the over/under for Raiders vs 49ers?
The median total across 15 sportsbooks is 51.5. Best available: Over 51 (-110, Circa) · Under 51.5 (-105, PointsBet).
What are the moneyline odds for Raiders vs 49ers?
The best available moneylines are Raiders (+410, FanDuel) · 49ers (-450, Fanatics).
Does KarmaEdge have an AI prediction for Raiders vs 49ers?
Not yet. No KarmaEdge AI projection is published for Raiders vs 49ers; games appear once the model is published for the slate. Nothing is filled in meanwhile.
Is KarmaEdge.AI a sportsbook?
No. KarmaEdge.AI is not a sportsbook and never accepts wagers. It is a research site that compares markets and shows KarmaEdge AI research next to them.
KarmaEdge.AI is not a sportsbook and never accepts wagers. Lines move; each shows when it was read. Projections are research, not guarantees. 18+ and of legal age where you are. Gambling problem? Call 1-800-GAMBLER.
Add KarmaEdge to your Home Screen