NFL · Prediction, odds & props

Buffalo Bills vs Minnesota Vikings Prediction & Odds

· U.S. Bank Stadium

Quick answer
  • Buffalo Bills (6-1) at Minnesota Vikings (6-1): kickoff Monday, November 9, 2026 at 8:15 PM ET, U.S. Bank Stadium.
  • Spread: Bills -3.5, the median of 12 sportsbooks. Best available: Bills -3 (-115, ESPN BET) · Vikings +3.5 (-115, Circa).
  • Total (over/under): 46.5. Best available: Over 45.5 (-110, Circa) · Under 46.5 (-105, ESPN BET).
  • Best moneyline: Bills (-169, theScore Bet) · Vikings (+155, BetMGM).
  • Lines as of Tue, Nov 3 · 10:18 AM ET; they move after that.

Bills vs Vikings odds

Best available moneyline, spread and total across 12 sportsbooks. Every book is one tap away.

10:18 AM ET
12 booksMoneylineSpreadTotal
Buffalo Bills -169 theScore Bet -3.0 -115 ESPN BET O 45.5 -110 Circa
Minnesota Vikings +155 BetMGM +3.5 -115 Circa U 46.5 -105 ESPN BET
View all sportsbooks (12)Eligible fresh comparisons
BookMoneylineSpreadTotal
Bally Bet -180+145 -3.0 -117+3.0 -105 O 46.5 -113U 46.5 -108
BetMGM -190+155 -3.5 -102+3.5 -118 O 46.0 -110U 46.0 -108
BetR Sportsbook -189+150 —— ——
BetRivers -180+145 -3.0 -117+3.0 -105 O 46.5 -113U 46.5 -108
Circa -180+155 -3.5 -105+3.5 -115 O 45.5 -110U 45.5 -110
DraftKings -185+154 -3.5 -102+3.5 -118 O 45.5 -115U 45.5 -105
ESPN BET -170+145 -3.0 -115+3.0 -105 O 46.5 -115U 46.5 -105
FanDuel -172+144 -3.0 -115+3.0 -105 O 46.5 -104U 46.5 -118
Hard Rock Bet -180+150 -3.5 -105+3.5 -115 O 46.5 -110U 46.5 -110
PointsBet -179+150 -3.5 +100+3.5 -120 O 45.5 -111U 45.5 -111
theScore Bet -169+145 -3.0 -115+3.0 -105 O 46.5 -115U 46.5 -105
Tipico -200+155 -3.5 -103+3.5 -125 O 46.5 -108U 46.5 -120

◆ Best: the most favorable fresh line, then price, for that exact side. Rows read Buffalo Bills first, then Minnesota Vikings.

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Bills vs Vikings AI prediction

The KarmaEdge AI spread and total projections next to the posted line, with the KarmaEdge AI Score.

No KarmaEdge AI projection is published for this game yetGames appear once the KarmaEdge AI model is published for the slate. Nothing is filled in meanwhile.

All NFL AI predictions →

Bills vs Vikings line movement

DraftKings lines from the open (or the first line KarmaEdge tracked) to now.

MarketSideOpen / first trackedNowMove
MoneylineBills -155.0 Open -185.0 -30
MoneylineVikings 130.0 Open 154.0 +24
SpreadBills -3.0 Open -3.5 -0.5
SpreadVikings 3.0 Open 3.5 +0.5
TotalOver 48.5 Open 45.5 -3
TotalUnder 48.5 Open 45.5 -3

Every NFL line move on Live Trends →

Bills vs Vikings player props

Current prop lines for this game: 12 of 26. Free line comparison; no picks or guarantees.

All Bills vs Vikings player props → · NFL player props today →

Bills vs Vikings on the field

Each team's listed starters in its base formation, from the depth charts as of Nov 3, 2026. Tap a player for the backups.

Vikings defense · Base 3-4

Bills offense · 11 personnel

Bills defense · Base 3-4

Vikings offense · 11 personnel

Buffalo Bills depth chart →   Minnesota Vikings depth chart →

Bills vs Vikings injury report

This game's injury reports are not out yet. The depth charts below carry each team's latest report.

Buffalo Bills depth chart →   Minnesota Vikings depth chart →

Frequently asked questions

What time is Bills vs Vikings?

Kickoff is Monday, November 9, 2026 at 8:15 PM ET at U.S. Bank Stadium.

What is the spread for Bills vs Vikings?

The median spread across 12 sportsbooks is Bills -3.5 as of Tue, Nov 3 · 10:18 AM ET. Best available by side: Bills -3 (-115, ESPN BET) · Vikings +3.5 (-115, Circa).

What is the over/under for Bills vs Vikings?

The median total across 12 sportsbooks is 46.5. Best available: Over 45.5 (-110, Circa) · Under 46.5 (-105, ESPN BET).

What are the moneyline odds for Bills vs Vikings?

The best available moneylines are Bills (-169, theScore Bet) · Vikings (+155, BetMGM).

Does KarmaEdge have an AI prediction for Bills vs Vikings?

Not yet. No KarmaEdge AI projection is published for Bills vs Vikings; games appear once the model is published for the slate. Nothing is filled in meanwhile.

Is KarmaEdge.AI a sportsbook?

No. KarmaEdge.AI is not a sportsbook and never accepts wagers. It is a research site that compares markets and shows KarmaEdge AI research next to them.

KarmaEdge.AI is not a sportsbook and never accepts wagers. Lines move; each shows when it was read. Projections are research, not guarantees. 18+ and of legal age where you are. Gambling problem? Call 1-800-GAMBLER.